We recommend using the Clinical Frailty Scale if the preoperative anaesthesia physical examination reveals the presence of a frailty phenotype. We should ask for an evaluation from ageriatrician toimprovethecognitive,nutritionalandcomorbidity statusbydelayingsurgery (time-sensitiveorelectiveprocedures) wheneverpossible. (1C)

We recommend using the Clinical Frailty Scale because of its high feasibility and predictive values. (1C)

The role of prehabilitation should be established in noncardiac surgery patients. (2B)

Nutritional support before surgery should be considered in noncardiac surgery patients. (2C)

We do not recommend routine admission to the ICU for patients with stable cardiac diseases undergoing elective major surgery. Selective access to the ICU in this subset of patients following a multidisciplinary evaluation of the risk-to-benefit ratio might be more appropriate. (1C)

When a GLP-1 agonist is prescribed as a weekly injection and considering the long half-life of GLP-1 agonists, we recommend pausing GLP-1 agonists at least 1 week before a scheduled procedure requiring sedation/anaesthesia. If these drugs are given for obesity, then 2 weeks (three half-lives) are recommended. (CPS)

If the medication is prescribed as daily oral or subcutaneous administration, we recommend pausing GLP-1 agonists on the day of the procedure. (CPS)

There is no evidence to show that stopping these medications even 1 week before the procedure will eliminate the risk of delayed gastric emptying, despite following the usual fasting timing for surgery. (CPS)