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[lyyw] => For patients undergoing neurosurgery, the target for intraoperative blood glucose control is 5.0–10.0 mmol/L and for postoperative blood glucose control is less than 12.0 mmol/L. On the basis of the target range, it is suggested that intraoperative blood glucose level is monitored every 1–2 h and postoperative blood glucose level is monitored every 2–4 h. (2C)
[laiyuan] => 对于接受神经外科手术的患者,术中血糖控制目标为5.0–10.0 mmol/L,术后血糖控制目标为小于12.0 mmol/ L 。根据目标范围,建议每隔1-2小时监测一次术中血糖水平,每隔2-4小时监测一次术后血糖水平。(证据级别:低;推荐强度:弱推荐)。
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推荐意见
对于接受神经外科手术的患者,术中血糖控制目标为5.0–10.0 mmol/L,术后血糖控制目标为小于12.0 mmol/ L 。根据目标范围,建议每隔1-2小时监测一次术中血糖水平,每隔2-4小时监测一次术后血糖水平。(证据级别:低;推荐强度:弱推荐)。
For patients undergoing neurosurgery, the target for intraoperative blood glucose control is 5.0–10.0 mmol/L and for postoperative blood glucose control is less than 12.0 mmol/L. On the basis of the target range, it is suggested that intraoperative blood glucose level is monitored every 1–2 h and postoperative blood glucose level is monitored every 2–4 h. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => For patients undergoing fine surgery (fine surgery is defined as a minimally invasive or microsurgical procedure requiring high precision, and the types include ophthalmic surgery, facial plastic surgery, among others), the target for preoperative blood glucose control is 5.0–7.2 mmol/L; for patients with a long disease course and those who have difficulty reaching the blood glucose standards, the target for blood glucose control may be increased up to <8.3 mmol/L. The target for intraoperative blood glucose control is 6.7–11.1 mmol/L and for postoperative blood glucose control is less than 12.0 mmol/L. On the basis of the suggested target range, intraoperative blood glucose level is monitored every 1–2 h and postoperative blood glucose level is monitored every 4–6 h. (2C)
[laiyuan] => 对于接受精细手术(精细手术被定义为需要高精度的微创或显微外科手术,类型包括眼科手术、面部整形手术等)的患者,术前血糖控制目标为5.0–7.2 mmol/L;对于病程较长的患者和难以达到血糖标准的患者,血糖目标控制可增加至< 8.3mmol/L。术中目标血糖控制在6.7–11.1mmol/L,术后血糖控制低于12.0mmol/L。根据建议的目标范围,术中血糖水平每1-2小时监测一次,术后血糖水平每4-6小时监测一次。(证据级别:低;推荐强度:弱推荐)。
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推荐意见
对于接受精细手术(精细手术被定义为需要高精度的微创或显微外科手术,类型包括眼科手术、面部整形手术等)的患者,术前血糖控制目标为5.0–7.2 mmol/L;对于病程较长的患者和难以达到血糖标准的患者,血糖目标控制可增加至< 8.3mmol/L。术中目标血糖控制在6.7–11.1mmol/L,术后血糖控制低于12.0mmol/L。根据建议的目标范围,术中血糖水平每1-2小时监测一次,术后血糖水平每4-6小时监测一次。(证据级别:低;推荐强度:弱推荐)。
For patients undergoing fine surgery (fine surgery is defined as a minimally invasive or microsurgical procedure requiring high precision, and the types include ophthalmic surgery, facial plastic surgery, among others), the target for preoperative blood glucose control is 5.0–7.2 mmol/L; for patients with a long disease course and those who have difficulty reaching the blood glucose standards, the target for blood glucose control may be increased up to <8.3 mmol/L. The target for intraoperative blood glucose control is 6.7–11.1 mmol/L and for postoperative blood glucose control is less than 12.0 mmol/L. On the basis of the suggested target range, intraoperative blood glucose level is monitored every 1–2 h and postoperative blood glucose level is monitored every 4–6 h. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => For patients undergoing emergency surgery, the target for blood glucose control is the same as that for patients undergoing the corresponding elective surgery; however,
intraoperative monitoring should be performed more frequently. (2C)
[laiyuan] => 对于接受急诊手术的患者,血糖控制的目标与接受相应的择期手术的患者相同;然而,术中监测应更频繁地进行。(证据级别:低;推荐强度:弱推荐)。
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推荐意见
对于接受急诊手术的患者,血糖控制的目标与接受相应的择期手术的患者相同;然而,术中监测应更频繁地进行。(证据级别:低;推荐强度:弱推荐)。
For patients undergoing emergency surgery, the target for blood glucose control is the same as that for patients undergoing the corresponding elective surgery; however,
intraoperative monitoring should be performed more frequently. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => For patients with gestational diabetes mellitus, the blood glucose control target ranges are as follows: blood glucose >3.3 mmol/L, fasting blood glucose <5.3 mmol/L, postprandial 1‐h blood glucose <7.8 mmol/L and postprandial 2‐h blood glucose <6.7 mmol/L for patients with pre‐pregnancy diabetes, the blood glucose control target can be individualization. (1B) Despite attempts to control their blood glucose levels through a combination of diet and exercise, if the maternal blood glucose levels in pregnant women do not meet the standard, it is suggested that insulin therapy is started. (2C) The blood glucose levels in the course of labour and childbirth should be controlled within 4–7 mmol/L and intraoperative and postoperative blood glucose levels should be controlled within 6.0–12.0 mmol/L. Blood glucose levels should be monitored every 30 min during this time. When the labour is prolonged and the blood glucose level is reduced to <6.0 mmol/L, an intravenous infusion of 5% glucose to increase the blood glucose is suggested. (2C)
[laiyuan] => 对于妊娠期糖尿病患者,血糖控制目标范围如下:血糖> 3.3 mmol/L,空腹血糖< 5.3 mmol/L,餐后1h血糖< 7.8 mmol/L,餐后2h血糖< 6.7 mmol/L对于孕前糖尿病患者,血糖控制目标可以个体化。(证据级别:中;推荐强度:强推荐)。尽管人们试图通过控制血糖水平饮食和运动相结合,如果孕妇母体血糖水平不达标,建议开始胰岛素治疗。(证据级别:低;推荐强度:弱推荐)。分娩过程中的血糖水平应控制在4-7 mmol/L,术中及术后血糖水平应控制在6.0-12.0 mmol/L。在此期间,应每30分钟监测一次血糖水平。当产程延长并且血糖水平降至< 6.0 mmol/L时,静脉输注5%葡萄糖以增加血液建议使用葡萄糖。(证据级别:低;推荐强度:弱推荐)。
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推荐意见
对于妊娠期糖尿病患者,血糖控制目标范围如下:血糖> 3.3 mmol/L,空腹血糖< 5.3 mmol/L,餐后1h血糖< 7.8 mmol/L,餐后2h血糖< 6.7 mmol/L对于孕前糖尿病患者,血糖控制目标可以个体化。(证据级别:中;推荐强度:强推荐)。尽管人们试图通过控制血糖水平饮食和运动相结合,如果孕妇母体血糖水平不达标,建议开始胰岛素治疗。(证据级别:低;推荐强度:弱推荐)。分娩过程中的血糖水平应控制在4-7 mmol/L,术中及术后血糖水平应控制在6.0-12.0 mmol/L。在此期间,应每30分钟监测一次血糖水平。当产程延长并且血糖水平降至< 6.0 mmol/L时,静脉输注5%葡萄糖以增加血液建议使用葡萄糖。(证据级别:低;推荐强度:弱推荐)。
For patients with gestational diabetes mellitus, the blood glucose control target ranges are as follows: blood glucose >3.3 mmol/L, fasting blood glucose <5.3 mmol/L, postprandial 1‐h blood glucose <7.8 mmol/L and postprandial 2‐h blood glucose <6.7 mmol/L for patients with pre‐pregnancy diabetes, the blood glucose control target can be individualization. (1B) Despite attempts to control their blood glucose levels through a combination of diet and exercise, if the maternal blood glucose levels in pregnant women do not meet the standard, it is suggested that insulin therapy is started. (2C) The blood glucose levels in the course of labour and childbirth should be controlled within 4–7 mmol/L and intraoperative and postoperative blood glucose levels should be controlled within 6.0–12.0 mmol/L. Blood glucose levels should be monitored every 30 min during this time. When the labour is prolonged and the blood glucose level is reduced to <6.0 mmol/L, an intravenous infusion of 5% glucose to increase the blood glucose is suggested. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => For patients in postoperative intensive care or under mechanical ventilation and patients without cardiovascular disease or liver and kidney dysfunction, the target blood glucose level is 7.8–10.0 mmol/L. For patients with cardiovascular and cerebrovascular disease or liver and kidney dysfunction, the target for blood glucose control is 8.0–12.0 mmol/L; however, the upper limit of the target blood glucose level can be extended up to 13.9 mmol/L. The blood glucose levels are monitored every 1–4 h. (2C)
[laiyuan] => 对于术后重症监护或机械通气的患者和无心血管疾病或肝肾功能障碍的患者,目标血糖水平为7.8–10.0 mmol/L,对于有心脑血管疾病或肝肾功能障碍的患者,血糖控制目标为8.0–12.0 mmol/L;但是,目标血糖水平的上限可延长至13.9mmol/L。每隔1-4小时监测一次血糖水平。(证据级别:低;推荐强度:弱推荐)。
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推荐意见
对于术后重症监护或机械通气的患者和无心血管疾病或肝肾功能障碍的患者,目标血糖水平为7.8–10.0 mmol/L,对于有心脑血管疾病或肝肾功能障碍的患者,血糖控制目标为8.0–12.0 mmol/L;但是,目标血糖水平的上限可延长至13.9mmol/L。每隔1-4小时监测一次血糖水平。(证据级别:低;推荐强度:弱推荐)。
For patients in postoperative intensive care or under mechanical ventilation and patients without cardiovascular disease or liver and kidney dysfunction, the target blood glucose level is 7.8–10.0 mmol/L. For patients with cardiovascular and cerebrovascular disease or liver and kidney dysfunction, the target for blood glucose control is 8.0–12.0 mmol/L; however, the upper limit of the target blood glucose level can be extended up to 13.9 mmol/L. The blood glucose levels are monitored every 1–4 h. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => The medical staff should strengthen awareness regarding the prevention of hypoglycaemia, timely identify the hypoglycaemic performance, strengthen the monitoring and management of hypoglycaemia and educate patients and their families on strategies for preventing hypoglycaemia. (1B)
[laiyuan] => 医务人员应加强预防低血糖的意识,及时识别低血糖的表现,加强对低血糖的监测和管理,并教育患者及其家属应对策略预防低血糖。(证据级别:中;推荐强度:强推荐)
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推荐意见
医务人员应加强预防低血糖的意识,及时识别低血糖的表现,加强对低血糖的监测和管理,并教育患者及其家属应对策略预防低血糖。(证据级别:中;推荐强度:强推荐)
The medical staff should strengthen awareness regarding the prevention of hypoglycaemia, timely identify the hypoglycaemic performance, strengthen the monitoring and management of hypoglycaemia and educate patients and their families on strategies for preventing hypoglycaemia. (1B)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => In case of hypoglycaemia, the need for intraoperative infusion of fluids and the dosage of insulin should be determined based on the blood glucose levels. When the blood glucose is between 5.6 and 10.0 mmol/L, no specialised treatment is required, and blood glucose monitoring every 2 h is recommended. Blood glucose below 5.6 mmol/l immediately stop intravenous insulin infusion. During the fasting state, when the blood glucose is less than 4.4 mmol/L, an intravenous injection of 10 g high glucose, and blood glucose monitoring every 15–30 min are recommended. When the blood glucose level is between 4.4 and 5.6 mmol/L, intravenous infusion of 5% glucose at 40 ml/h or 10% glucose at 20 ml/h and blood glucose monitoring every 1 h are recommended . If hypoglycaemia occurs during the nonfasting state, patients are advised to take 10–25 g of glucose orally for rapid absorption of carbohydrates (such as glucose‐based drinks). For patients who are unable to consume oral glucose, an intravenous injection of 20–50 ml of 50% glucose, followed by continuous intravenous infusion of 5% or 10% glucose are used to maintain the blood glucose levels. Blood glucose levels are monitored every 15 min until it reaches ≥5.6 mmol/L. (2C)
[laiyuan] => 在低血糖的情况下,应根据血糖水平确定术中补液的需要和胰岛素的剂量。当血糖在5.6到10.0mmol/l之间时,不需要特殊治疗,建议每2h监测一次血糖。血糖低于5.6 mmol/l立即停止静脉输注胰岛素。在禁食状态下,当血糖低于4.4 mmol/L时,建议静脉注射10 g高葡萄糖,并每隔15-30min监测一次血糖。当血糖水平在4.4和5.6mmol/L之间时,建议以40ml/h的速度静脉输注5%葡萄糖或以20ml/h的速度静脉输注10%葡萄糖,并每隔1h监测一次血糖。如果在非禁食状态下出现低血糖,建议患者口服10-25g葡萄糖,以快速吸收碳水化合物(如葡萄糖饮料)。对于不能口服葡萄糖的患者,静脉注射20-50ml50%的葡萄糖,然后持续静脉输注5%或10%的葡萄糖,以维持血糖水平。血糖水平每隔15min,直到达到≥5.6mmol/L。(证据级别:低;推荐强度:弱推荐)。
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)
推荐意见
在低血糖的情况下,应根据血糖水平确定术中补液的需要和胰岛素的剂量。当血糖在5.6到10.0mmol/l之间时,不需要特殊治疗,建议每2h监测一次血糖。血糖低于5.6 mmol/l立即停止静脉输注胰岛素。在禁食状态下,当血糖低于4.4 mmol/L时,建议静脉注射10 g高葡萄糖,并每隔15-30min监测一次血糖。当血糖水平在4.4和5.6mmol/L之间时,建议以40ml/h的速度静脉输注5%葡萄糖或以20ml/h的速度静脉输注10%葡萄糖,并每隔1h监测一次血糖。如果在非禁食状态下出现低血糖,建议患者口服10-25g葡萄糖,以快速吸收碳水化合物(如葡萄糖饮料)。对于不能口服葡萄糖的患者,静脉注射20-50ml50%的葡萄糖,然后持续静脉输注5%或10%的葡萄糖,以维持血糖水平。血糖水平每隔15min,直到达到≥5.6mmol/L。(证据级别:低;推荐强度:弱推荐)。
In case of hypoglycaemia, the need for intraoperative infusion of fluids and the dosage of insulin should be determined based on the blood glucose levels. When the blood glucose is between 5.6 and 10.0 mmol/L, no specialised treatment is required, and blood glucose monitoring every 2 h is recommended. Blood glucose below 5.6 mmol/l immediately stop intravenous insulin infusion. During the fasting state, when the blood glucose is less than 4.4 mmol/L, an intravenous injection of 10 g high glucose, and blood glucose monitoring every 15–30 min are recommended. When the blood glucose level is between 4.4 and 5.6 mmol/L, intravenous infusion of 5% glucose at 40 ml/h or 10% glucose at 20 ml/h and blood glucose monitoring every 1 h are recommended . If hypoglycaemia occurs during the nonfasting state, patients are advised to take 10–25 g of glucose orally for rapid absorption of carbohydrates (such as glucose‐based drinks). For patients who are unable to consume oral glucose, an intravenous injection of 20–50 ml of 50% glucose, followed by continuous intravenous infusion of 5% or 10% glucose are used to maintain the blood glucose levels. Blood glucose levels are monitored every 15 min until it reaches ≥5.6 mmol/L. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => During minor and moderate surgeries (i.e., surgery time shorter than 1 h), it is not necessary to perform insulin therapy for patients with diabetes if the blood glucose levels are adequately controlled by the previously administered oral antidiabetic agents. (1B) Glucosidase inhibitors, DPP-IV inhibitors, GLP-1 analogues and PPAR-γ receptor agonists can be administered according to routine. During the fasting period, agents with high risk of causing hypoglycaemia, such as sulfonylurea drugs and non‐sulfonylurea insulin secretagogues should be stopped. (1B) Sodium–glucose cotransporter 2 (SGLT2) inhibitors should be avoided in case of surgical procedures. (2B)
[laiyuan] => 在小手术和中等手术期间(即手术时间短于1小时),如果糖尿病患者的血糖水平已被之前服用的口服降糖药充分控制,则没有必要对其进行胰岛素治疗。(证据级别:中;推荐强度:强推荐)。葡萄糖苷酶抑制剂、DPP‐IV抑制剂、GLP‐1类似物和PPAR‐γ受体激动剂可按照常规给药。在禁食期间,应停用磺酰脲类药物和非磺酰脲类胰岛素促分泌素等高低血糖风险药物(1B)。外科手术中应避免使用钠-葡萄糖协同转运蛋白2 (SGLT2)抑制剂。(证据级别:中;推荐强度:弱推荐)
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推荐意见
在小手术和中等手术期间(即手术时间短于1小时),如果糖尿病患者的血糖水平已被之前服用的口服降糖药充分控制,则没有必要对其进行胰岛素治疗。(证据级别:中;推荐强度:强推荐)。葡萄糖苷酶抑制剂、DPP‐IV抑制剂、GLP‐1类似物和PPAR‐γ受体激动剂可按照常规给药。在禁食期间,应停用磺酰脲类药物和非磺酰脲类胰岛素促分泌素等高低血糖风险药物(1B)。外科手术中应避免使用钠-葡萄糖协同转运蛋白2 (SGLT2)抑制剂。(证据级别:中;推荐强度:弱推荐)
During minor and moderate surgeries (i.e., surgery time shorter than 1 h), it is not necessary to perform insulin therapy for patients with diabetes if the blood glucose levels are adequately controlled by the previously administered oral antidiabetic agents. (1B) Glucosidase inhibitors, DPP-IV inhibitors, GLP-1 analogues and PPAR-γ receptor agonists can be administered according to routine. During the fasting period, agents with high risk of causing hypoglycaemia, such as sulfonylurea drugs and non‐sulfonylurea insulin secretagogues should be stopped. (1B) Sodium–glucose cotransporter 2 (SGLT2) inhibitors should be avoided in case of surgical procedures. (2B)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => Patients under intraoperative insulin therapy should continue to receive insulin therapy during the postoperative fasting period (24–48 h) until they start eating, following which oral anti‐diabetic agents can be resumed. (2C)
[laiyuan] => 术中接受胰岛素治疗的患者应在术后禁食期间(24-48小时)继续接受胰岛素治疗,直到他们开始进食,之后可恢复口服抗糖尿病药物。(证据级别:低;推荐强度:弱推荐)
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推荐意见
术中接受胰岛素治疗的患者应在术后禁食期间(24-48小时)继续接受胰岛素治疗,直到他们开始进食,之后可恢复口服抗糖尿病药物。(证据级别:低;推荐强度:弱推荐)
Patients under intraoperative insulin therapy should continue to receive insulin therapy during the postoperative fasting period (24–48 h) until they start eating, following which oral anti‐diabetic agents can be resumed. (2C)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen
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[lyyw] => People with diabetes with normal renal function do not need to stop taking metformin before surgery. (2B) However, if the use of an intraoperative iodine contrast agent is necessary, metformin should not be taken 24 h before surgery. For patients with abnormal renal function, metformin should not be taken 48 h before surgery if using an iodine contrast agent and general anaesthesia, and it's administration should be suspended for 48–72 h postsurgery until renal function is normal. (2B) Metformin is not recommended when the glomerular filtration rate (eGFR) is 30–45 ml/(min•1.73 m2 ), and is prohibited when eGFR<30 ml/(min•1.73 m2). (1A)
[laiyuan] => 肾功能正常的糖尿病患者在手术前不需要停止服用二甲双胍。(证据级别:中;推荐强度:弱推荐)。但是,如果术中必须使用碘造影剂,则不应在手术前24小时服用二甲双胍。对于肾功能异常的患者,如果使用碘造影剂和全身麻醉,则不应在术前48小时服用二甲双胍,并且应在术后48-72小时暂停服用二甲双胍,直至肾功能正常(证据级别:中;推荐强度:弱推荐)。二甲双胍不推荐当肾小球滤过率(eGFR)为30–45ml/(min 1.73 m2),当eGFR < 30ml/(min 1.73 m2)时禁用。(证据级别:高;推荐强度:强推荐)。
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推荐意见
肾功能正常的糖尿病患者在手术前不需要停止服用二甲双胍。(证据级别:中;推荐强度:弱推荐)。但是,如果术中必须使用碘造影剂,则不应在手术前24小时服用二甲双胍。对于肾功能异常的患者,如果使用碘造影剂和全身麻醉,则不应在术前48小时服用二甲双胍,并且应在术后48-72小时暂停服用二甲双胍,直至肾功能正常(证据级别:中;推荐强度:弱推荐)。二甲双胍不推荐当肾小球滤过率(eGFR)为30–45ml/(min 1.73 m2),当eGFR < 30ml/(min 1.73 m2)时禁用。(证据级别:高;推荐强度:强推荐)。
People with diabetes with normal renal function do not need to stop taking metformin before surgery. (2B) However, if the use of an intraoperative iodine contrast agent is necessary, metformin should not be taken 24 h before surgery. For patients with abnormal renal function, metformin should not be taken 48 h before surgery if using an iodine contrast agent and general anaesthesia, and it's administration should be suspended for 48–72 h postsurgery until renal function is normal. (2B) Metformin is not recommended when the glomerular filtration rate (eGFR) is 30–45 ml/(min•1.73 m2 ), and is prohibited when eGFR<30 ml/(min•1.73 m2). (1A)
证据评价方法:GRADE
指南质量等级:A
年份:2021
国家:Guideline Steering Group, the Guideline Developmen